[PDF.97dr] Population Pharmacokinetics of Phenytoin in Epileptic Patients: Population Pharmacokinetics of Phenytoin in Epileptic Patients- A preliminary Study

Population Pharmacokinetics of Phenytoin in Epileptic Patients: Population Pharmacokinetics of Phenytoin in Epileptic Patients- A preliminary Study

[PDF.fx48] Population Pharmacokinetics of Phenytoin in Epileptic Patients: Population Pharmacokinetics of Phenytoin in Epileptic Patients- A preliminary Study

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 |  2011-03-29 | Original language:English | PDF # 1 |  8.66 x.20 x5.91l,.31 | File type: PDF | 88 pages

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||About the Author|Mr. Ramjan Shaik is a lecturer in the Dept. of Pharmacy Practice, Al-Ameen College of Pharmacy, Bangalore, India. He has national and international presentations and publications to his credit, co- authored two chapters in textbook entitled ?E

Phenytoin exhibits non-linear pharmacokinetics, narrow therapeutic index, marked inter-individual variations and causes wide variety of adverse effects which warrants the need for monitoring. The present study was taken up to monitor serum concentrations and to carry out preliminary pharmacokinetic modelling. HPLC method was standardized to estimate the serum concentration of phenytoin. Blood samples were withdrawn from the patients after the steady state has be...

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